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Discovering Genetic Variation that Affects Expression in Multiple Tissues

Over the past several years, Genome Wide Association Studies (GWAS) have discovered hundreds of genetic variants involved in complex diseases[1].  The vast majority of these variants do not lie in the...

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Dr. Jae Hoon Sul Thesis Defense Talk

Dr. Jae Hoon Sul with his committee. Jae Hoon Sul successfully defended his thesis on Wednesday September 19th.  His talk is posted on our YouTube Channel ZarlabUCLA.  Jae Hoon’s talk discusses...

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Emrah Kostem’s talk about his research

Emrah Kostem, who graduated this year and is now at Illumina, gave a talk about the research he completed in the lab this summer at our retreat.  It is available here and gives a good overview of what...

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Hypothalamic transcriptomes of 99 mouse strains reveal trans eQTL hotspots,...

In a recent project, Farhad Hormozdiari and Eleazar Eskin contributed data analysis and interpretation to a project identifying new genes and genomic regions associated with metabolic function in...

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Incorporating prior information into association studies

Genome-wide association studies (GWAS) seek to identify genetic variants involved in specific traits. GWAS are advantageous for linking variants with traits, because they interrogate the genome in a...

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Widespread Allelic Heterogeneity in Complex Traits

This week, our group published a paper in the American Journal of Human Genetics that presents a new computational method for improving the accuracy of genome wide association studies. ZarLab alumni...

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Fine Mapping Causal Variants and Allelic Heterogeneity

On Friday, April 28, 2017, in the CNSI Auditorium, Eleazar Eskin presented ZarLab’s research on fine mapping causal variants and allelic heterogeneity at the 2nd Annual Institute for Quantitative and...

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